We’ve sliced and diced our portfolio into distinct “trends” that define our edge.
We are pleased to report that as of April 2021 the SOSV Climate Tech 100 have raised $1.85 billion from investors and have a market cap of $5.65 billion. The average company is four years old. SOSV (our parent fund) has invested $89 million in these companies and was in most cases the first investor, though we continued investing through early rounds.
IndieBio has never been one to shy away from the riskiest and most impactful investments for our planet. In fact, we embrace them.
Boosting female representation in the startup world is an ongoing challenge, but we’re dedicated to gender balance, not only because it’s the right thing to do, but because we would be dismissing impressive companies otherwise. We’ve found that more gender balance leads to better workplace culture and better ideas being exchanged.
Future of Food
It’s not just that we can make meat and fish in the lab, or with mushrooms and chickpeas. It’s not just that AI can predict the best plant ingredients to make the best tasting milk and yogurt. And it’s not just that yeast can be fermented to produce the healthier and better food preservatives. We’re diving deep every day into the foods that will satisfy novelty-seekers and conventionalists alike.
We’re putting big bets on the newest technologies and trends we think are ahead of the curve.
Future of Medicine
Medicine ain’t what it used to be. Today, bloodletting, skull-drilling and giving children cocaine for toothaches are relics of the past. Tomorrow, so too will addictive opioids, chemotherapy, and psychiatric drugs that are non-selectively bathing our bodies in chemicals.
The future of medicine is an exciting one, and we’re excited to share the most exciting technologies that enable the next wave of medicine and healthcare.
Our mission has always been Human and Planetary Health from the beginning, so it’s hard to say which of our companies are “impact” companies (in some ways, they all are).
Here, we narrowed down the startups that are directly addressing sustainability issues, improving public health, mitigating inequality, and democratizing access to infrastructure and technologies.
Every season of the year, a new batch and about one-sixth of our alumni are in raise mode. These companies are currently raising and would love to talk to interested investors. We can set up those meetings or you can contact the companies directly.
Oil wells are not the first thing you think of when you think of lithium sources, but pumping oil out of the ground actually requires a lot of water, either to fracture the rock or to push out the oil of old wells. That water is often locally sourced from deep underground, and has to […]
Ethanol may be 10% of every gas tank, but the economics of making ethanol have become marginal. VIA Fuels enables ethanol plants to use their existing infrastructure and feedstocks to make much more valuable and versatile drop-in, carbon neutral fuels. Unlike ethanol, VIA Fuels can be blended at higher rates to create renewable fuels for […]
Karma Biotech is an oncology company targeting solid tumors, starting with colorectal cancer. Their technology aims to deliver cytokines and other biologicals, such as IL-15, specifically to tumor and metastatic sites, avoiding the dangers of systemic toxicity. This localized IL-15 will turn cold tumors hot, allowing the body to clear the cancer. The founders at […]
Four years ago, Ben Slotnick was on the technical evaluation team for one of the largest carbon-capture-and-storage projects in the world, pumping CO2 under the North Sea. He came to the conclusion that spending over $1 billion in capex before sequestering any CO2 was the wrong path. And it was the wrong way to use […]
Despite a decade of innovation into new eco-friendly textile fibers, none of them work on the huge melt-spun fiber machines that enable low costs. 70% of the fibers used by the apparel industry are made by melt-spinning. The result is that virtually all fiber innovation is hindered by costs 2x to 3x higher than petroleum-based […]
A wide number of cancers exhibit misregulated genome packaging at the chromatin level. If chromatin that should be tightly condensed, becomes loosely packed (or vice-versa), the normal brakes on cell growth aren’t operant, leading to uncontrolled cell growth. Being able to regulate and control the chromatin state has been a high-value target for oncology. Coming […]
Discovery of CAR-T cell-based therapies has transformed the treatment landscape for blood cancer patients. Still, the process to achieve this is “one patient – one batch”, limiting manufacturing scalability with high patient-to-patient variability. Moreover, complicated supply chain issues and associated high cost add to the hurdles of providing access to a larger population. On the […]
Viruses have evolved to become shapeshifters that can evade and distract our immune system by hiding some of their most vulnerable sites. History has shown that pandemics are not only lethal but also inevitable. Currently, the vaccines we know best poorly protect against pandemics and other viral outbreaks and leave many at-risk populations unprotected. By […]
Sustainable weight management involves adopting long-term lifestyle changes, including balanced nutrition and a focus on overall health. Traditional dieting methods and current drugs prioritize short-term weight loss and do not address the core issue of weight gain—the consumption of refined carbohydrates and sugar-laden foods. Palate Therapeutics is a new type of therapeutic company that aims […]
Since the start of the COVID-19 pandemic, telehealth usage has been up over 500%, yet little progress has been made to advance this critical technology. While a video call can offer unprecedented access to your physician, it is subjective by nature and, in its current form, cannot offer much in the way of diagnosis and […]