Featured Trends
We’ve sliced and diced our portfolio into distinct “trends” that define our edge.
Climate 100
We are pleased to report that as of April 2021 the SOSV Climate Tech 100 have raised $1.85 billion from investors and have a market cap of $5.65 billion. The average company is four years old. SOSV (our parent fund) has invested $89 million in these companies and was in most cases the first investor, though we continued investing through early rounds.
IndieBio has never been one to shy away from the riskiest and most impactful investments for our planet. In fact, we embrace them.
Female Founder
Boosting female representation in the startup world is an ongoing challenge, but we’re dedicated to gender balance, not only because it’s the right thing to do, but because we would be dismissing impressive companies otherwise. We’ve found that more gender balance leads to better workplace culture and better ideas being exchanged.
Future of Food
It’s not just that we can make meat and fish in the lab, or with mushrooms and chickpeas. It’s not just that AI can predict the best plant ingredients to make the best tasting milk and yogurt. And it’s not just that yeast can be fermented to produce the healthier and better food preservatives. We’re diving deep every day into the foods that will satisfy novelty-seekers and conventionalists alike.
We’re putting big bets on the newest technologies and trends we think are ahead of the curve.
Future of Medicine
Medicine ain’t what it used to be. Today, bloodletting, skull-drilling and giving children cocaine for toothaches are relics of the past. Tomorrow, so too will addictive opioids, chemotherapy, and psychiatric drugs that are non-selectively bathing our bodies in chemicals.
The future of medicine is an exciting one, and we’re excited to share the most exciting technologies that enable the next wave of medicine and healthcare.
Impact
Our mission has always been Human and Planetary Health from the beginning, so it’s hard to say which of our companies are “impact” companies (in some ways, they all are).
Here, we narrowed down the startups that are directly addressing sustainability issues, improving public health, mitigating inequality, and democratizing access to infrastructure and technologies.
New Frontiers
Raising Now
Every season of the year, a new batch and about one-sixth of our alumni are in raise mode. These companies are currently raising and would love to talk to interested investors. We can set up those meetings or you can contact the companies directly.
Sustainable Solutions
In the last few years, aptamers linked to CRISPR have brought programmable logic to drug design. However, the logic is primitive – once turned on, CRISPR remains on. Wayfinder is working on RNA-biosensors so that drugs can continuously sense their microenvironment, and turn modalities like CRISPR both on and off in response to what they […]
All available sunscreen active ingredients absorb through our skin, interfering with hormones and even exacerbating UV damage. Meanwhile, SPFs in cosmetics, washed down the drain at night, accumulate in sensitive marine environments, where even the “reef safe” versions threaten endangered corals and marine life. Based on groundbreaking work in protein engineering at Princeton, Soliome has […]
Pesticides are always a compromise: if you kill the mosquitos, you end up killing the bees too. Pyrone discovered a rare natural compound that controls mosquitos and other pests not by killing them, but by temporarily stunning them. Already fast-tracked by the EPA and being tested by the USDA in Gainesville, Pyrone is now scaling […]
There’s thousands of ways that cells become unhealthy. But until 2012, there were only two ways that cells actually die. That year, the cofounder of Prothegen, Dr. Scott Dixon, discovered a new way cells die, called ferroptosis, an iron-mediated failure of antioxidant defenses. Now Dixon has partnered with Roche alum Davide Zanchi and chemist Derek […]
In the field of liquid biopsy, the abundance of new technologies are mere screening tests. They can’t monitor patients’ progression and drive clinical decisions. The real money is in monitoring disease patients, for years. Atomic Force Microscopy scans the surface of cells at such high resolution that it can not only discriminate cancer cells from […]
Solid Ox is building Range Extenders for commercial fleets of electric trucks and buses. These range extenders use liquid fuel, where the CO2 is captured on board, right back into the fuel tank. Emissions-free. Commercial fleets that need long range are very price sensitive to fueling costs. They also run day and night, so have […]
The market value of farmland is driven by yield. For example, increasing soy yield by 10 bushels an acre can double the value of the farmland. Puna Bio repairs soil health using extremophiles – organisms 3.5 billion years old, sourced from La Puna, the highest and driest desert on Earth. These organisms grow where others […]
Potassium controls every single heartbeat you have, but it’s the kidneys that control your potassium levels. You could say the kidneys are the gatekeeper to your heart. Kidney care is going through dramatic market disruption. Home dialysis is displacing clinics. And patient care management companies are siphoning off patients. Nevertheless, these patients are still ending […]
In the canon of cultured meat, it’s all about reducing the cost of the Growth Factors. Grand Bio defies this doctrine. It’s like the cars we all drive. You can reduce the cost of gas. Or you can help the car drive farther on a gallon. Grand Bio sells affordable media supplements. Their activators can […]
Modern lifestyles are hard on our livers and kidneys, the organs that filter and break down metabolic waste products. But people don’t want to take drugs – they want to get healthy. Unlock unleashes the power of the microbiome to help out. Unlocked is a consumer probiotic company that unlocks silent genes – regaining the […]