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Featured Trends

We’ve sliced and diced our portfolio into distinct “trends” that define our edge.

Featured Trends

Climate 100

We are pleased to report that as of April 2021 the SOSV Climate Tech 100 have raised $1.85 billion from investors and have a market cap of $5.65 billion. The average company is four years old. SOSV (our parent fund) has invested $89 million in these companies and was in most cases the first investor, though we continued investing through early rounds.

IndieBio has never been one to shy away from the riskiest and most impactful investments for our planet. In fact, we embrace them.

SEE 59 COMPANIES
Climate 100
We have always been climate first, and here are SOSV’s select 100 startups saving our planet
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Featured Trends

Female Founder

Boosting female representation in the startup world is an ongoing challenge, but we’re dedicated to gender balance, not only because it’s the right thing to do, but because we would be dismissing impressive companies otherwise. We’ve found that more gender balance leads to better workplace culture and better ideas being exchanged.

SEE 70 COMPANIES
Female Founder
42% of our companies are led by women, and they’re killing it
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Featured Trends

Future of Food

It’s not just that we can make meat and fish in the lab, or with mushrooms and chickpeas. It’s not just that AI can predict the best plant ingredients to make the best tasting milk and yogurt. And it’s not just that yeast can be fermented to produce the healthier and better food preservatives. We’re diving deep every day into the foods that will satisfy novelty-seekers and conventionalists alike.

We’re putting big bets on the newest technologies and trends we think are ahead of the curve.

SEE 33 COMPANIES
Future of Food
We’re seeing next biggest food trends that nobody else is seeing
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Featured Trends

Future of Medicine

Medicine ain’t what it used to be. Today, bloodletting, skull-drilling and giving children cocaine for toothaches are relics of the past. Tomorrow, so too will addictive opioids, chemotherapy, and psychiatric drugs that are non-selectively bathing our bodies in chemicals.

The future of medicine is an exciting one, and we’re excited to share the most exciting technologies that enable the next wave of medicine and healthcare.

SEE 50 COMPANIES
Future of Medicine
Imagine what medicine will look like just 10 years from now
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Featured Trends

Impact

Our mission has always been Human and Planetary Health from the beginning, so it’s hard to say which of our companies are “impact” companies (in some ways, they all are).

Here, we narrowed down the startups that are directly addressing sustainability issues, improving public health, mitigating inequality, and democratizing access to infrastructure and technologies.

SEE 41 COMPANIES
Impact
Deep science + Deep mission = Deep impact
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Featured Trends

New Frontiers

SEE 5 COMPANIES
New Frontiers
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Featured Trends

Raising Now

Every season of the year, a new batch and about one-sixth of our alumni are in raise mode. These companies are currently raising and would love to talk to interested investors. We can set up those meetings or you can contact the companies directly.

SEE 40 COMPANIES
Raising Now
These companies are currently raising and would love to talk to interested investors.
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Featured Trends

Sustainable Solutions

SEE 21 COMPANIES
Sustainable Solutions
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Category
Trends
Stage
Top Location
Cohorts
IBNY05 2022
FluoSphera

Drug development costs over $2 billion per drug with a failure rate of 90% because in vitro methods do not mimic the systemic organization of the human body and animal models are too different from Humans. As a result, the limitations of in vitro testing reduce the probability to develop safe and efficient drugs for patients needing them and […]

HQ: Switzerland
Biopharma Healthcare Seed Future of Medicine Europe
IBSF05 2017
Prellis Biologics

World’s fastest high-resolution printer, printed with lasers, nanometers at at time.

HQ: United States
Biopharma Healthcare Series B+ Female Founder Future of Medicine San Francisco
IBSF07 2018
Filtricine

Undergoing clinical studies at Stanford right now in prostate cancer, Filtricine

HQ: United States
Biopharma Series A Female Founder Future of Medicine Impact San Francisco
IBSF03 2016
SyntheX

Drug discovery platform to inhibit protein-protein interactions

HQ: United States
Biopharma Series A Female Founder Future of Medicine San Francisco
IBNY05 2022
Vitarka Therapeutics

A new wave of RNA therapeutics has the potential to transform treatment for solid tumours. Existing non-viral technologies cannot target tumour cells. Moreover, these fail to release the therapeutic RNA into the cytosol, less than 1% leaks out of the endosomes (a sub-cellular compartment). The remaining 99% is degraded. EndoPore is Vitarka Therapeutics’ solution to […]

HQ: United Kingdom
Biopharma Healthcare Seed Female Founder Future of Medicine London
IBSF13 2022
Dandelion

To reach the full potential of RNA therapeutics, we have to understand how the tuning of just 4 ingredients in the delivery vehicle (lipid nanoparticles) can confer transfection and targeting efficiency. Dandelion is the first to leverage machine learning and biophysics in a systematic attempt to make sense of the chaos between LNP structure and […]

HQ: United States
Biopharma Computational/AI Pre-Seed Future of Medicine Massachusetts San Francisco
IBNY04 2022
ArgenTAG

Single-cell genomics has continued to undergo enormous progress since its inception more than a decade ago. Named twice as Method of the Year by the journal Nature, it continues to evolve with this innovation delivered by ArgenTAG.  ArgenTAG has developed the first truly scalable single-cell solution for long-read sequencers. The company has fundamentally changed the […]

HQ: Argentina
Biopharma Healthcare Pre-Seed Future of Medicine New Frontiers Latin America
IBSF13 2022
Laguna Bio

Laguna Bio is perfecting an entirely new approach to selectively activate and expand a specific type of T cell, the gamma-delta T (γδ T) cells, to take full advantage of the immune system’s ability to fight solid tumors. The γδ T cells are an obscure but homogeneous population of immune cells that you can count […]

HQ: United States
Biopharma Pre-Seed Future of Medicine USA
IBSF09 2019
Intrinsic Medicine (fka Lupa Bio)

Advancing two phase 2-ready clinical assets. Pioneering an untapped therapeutic modality. Working with the intelligence of nature. Creating the next generation of essential medicines

HQ: United States
Biopharma Seed Future of Medicine Impact
IBSF12 2021
Wayfinder Biosciences

In the last few years, aptamers linked to CRISPR have brought programmable logic to drug design. However, the logic is primitive – once turned on, CRISPR remains on. Wayfinder is working on RNA-biosensors so that drugs can continuously sense their microenvironment, and turn modalities like CRISPR both on and off in response to what they […]

HQ: United States
Biopharma Computational/AI Industrial Pre-Seed Future of Medicine New Frontiers Raising Now San Francisco
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