Featured Trends
We’ve sliced and diced our portfolio into distinct “trends” that define our edge.
Climate 100
We are pleased to report that as of April 2021 the SOSV Climate Tech 100 have raised $1.85 billion from investors and have a market cap of $5.65 billion. The average company is four years old. SOSV (our parent fund) has invested $89 million in these companies and was in most cases the first investor, though we continued investing through early rounds.
IndieBio has never been one to shy away from the riskiest and most impactful investments for our planet. In fact, we embrace them.
Female Founder
Boosting female representation in the startup world is an ongoing challenge, but we’re dedicated to gender balance, not only because it’s the right thing to do, but because we would be dismissing impressive companies otherwise. We’ve found that more gender balance leads to better workplace culture and better ideas being exchanged.
Future of Food
It’s not just that we can make meat and fish in the lab, or with mushrooms and chickpeas. It’s not just that AI can predict the best plant ingredients to make the best tasting milk and yogurt. And it’s not just that yeast can be fermented to produce the healthier and better food preservatives. We’re diving deep every day into the foods that will satisfy novelty-seekers and conventionalists alike.
We’re putting big bets on the newest technologies and trends we think are ahead of the curve.
Future of Medicine
Medicine ain’t what it used to be. Today, bloodletting, skull-drilling and giving children cocaine for toothaches are relics of the past. Tomorrow, so too will addictive opioids, chemotherapy, and psychiatric drugs that are non-selectively bathing our bodies in chemicals.
The future of medicine is an exciting one, and we’re excited to share the most exciting technologies that enable the next wave of medicine and healthcare.
Impact
Our mission has always been Human and Planetary Health from the beginning, so it’s hard to say which of our companies are “impact” companies (in some ways, they all are).
Here, we narrowed down the startups that are directly addressing sustainability issues, improving public health, mitigating inequality, and democratizing access to infrastructure and technologies.
New Frontiers
Raising Now
Every season of the year, a new batch and about one-sixth of our alumni are in raise mode. These companies are currently raising and would love to talk to interested investors. We can set up those meetings or you can contact the companies directly.
Sustainable Solutions
If you’ve got an investment in a startup doing high-throughput AI + biology, your startup is probably spending way too much for having DNA variant libraries printed. Synplexity should be their vendor of choice. At the intersection of AI and biotech, there’s a bottleneck. It’s not the design function powered by AI to generate 10 […]
Dr. Sethi’s approach rewrites the entire treatment playbook. Her protocol deftly navigates the complex interactions between diet and psychiatric medications, optimizing treatment while minimizing side effects. She’s currently working with 30 lucky clients, who got ahead of the long waitlist, but she wants to scale her practice 1000-fold. Four major insurers have credentialed MPL, and […]
Minutia is pioneering a functional cure for Type I Diabetes (T1D) that will allow patients to live without insulin injections and not suffer the long-term complications of the disease. Founded in 2021 out of UCSF, Minutia has already raised $13.5M, $6.5M in pre-seed SAFEs and $7M in grants, and has derisked the safety of their […]
Let’s talk DNA repair. Within 5 minutes of being in the sun, the energy of the solar photons introduces a small crack in the DNA of your skin cells. It’s not a random crack, it wears down the bonds at the 2 weakest points. One crack is called “CPD.” The other crack is called “6-4.” […]
To treat metastatic cancer, a radiotherapeutic must deliver a potent isotope to the tumor and keep it there long enough to kill the cancer, but clear quickly enough to avoid harming healthy tissue. So far, few radiotherapeutics have managed to meet both requirements. Boston-based Asta Bio aims to overcome these challenges with 211-Astatine—the most druggable […]
Medical researchers have genetically modified T cells to recognize and attack cancers, but they’ve run into some obstacles. Chimeric antigen receptor T (CAR-T) therapies are expensive ($373-475K per treatment), ineffective against solid tumors, potentially neurotoxic, and require gene editing if they’re sourced from healthy donors. That severely limits their potential for commercialization. Tinkeso Therapeutics is […]
Extending the human health span has long been a visionary goal for humanity, and Hexembio is at the forefront of achieving it. The company is revolutionizing aging and disease prevention by rejuvenating Hematopoietic Stem Cells (HSCs), also known as blood stem cells. This breakthrough offers exciting new possibilities for approaching age-related decline and chronic diseases, […]
Every year, 2 million people develop corneal blindness, but only about 200,000 undergo a corneal transplantation to regain their vision. Almost 13 million people are on waiting lists for donor tissue, and even if they obtain it, the rejection rate for corneal replacements climbs from 10% in the first two years to almost 50% by […]
Why we invested: At a small networking event, the founders said softly to us: “we are working on a technology that can completely upend the entire sequencing industry.” We leaned in to listen; after all, the founders have been working the front lines during every major pivotal point in sequencing history: Illumina’s acquisition of Solexa […]
Why we invested: The biggest risk in cancer immunotherapy is the safety: the cancer targets (i.e., neoantigens) are not differentiated enough from healthy cells, and can therefore lead to the immune system attacking the patient’s. When we met Dr. Corey Dambacher (the founder of Rybodyn), he said he has been sitting on a treasure trove […]