Applications for San Francisco (Batch 12) extended AGAIN through September 30th, 2021!

Mehdi Javanmard, Ph.D., CEO
Blood is probably the most informative bio-fluid that our body has, in which you can find something related to every system or systemic condition.
Bringing blood analysis to patients' fingertips
Detecting bacterial infections within minutes instead of days.

Antimicrobial resistance, resulting from overuse of antibiotics, is the greatest threat facing humankind in the 21st century. The RizLab Health mission is to build a point-of-care analyzer that can discriminate between viral and bacterial infections within minutes using only a single drop of blood. RizLab combines micro-chip technology with AI to build a pain-less platform that can within minutes aid physicians determine when their patients need antibiotics.

Betty Tang, CEO
Most plant-based milk alternatives only have one or two grams of protein, if any. A better solution would be a product that not only tasted good but was healthier and better for the environment.
Plant-based goods to nourish our world
Oatmilk uses 12 times less water than dairy and 7 times less water than almond milk to produce.

Upright is on a mission to make delicious foods that are better for people and our planet. Their first product is a category-defining high-protein, allergen-free instant oatmilk in three creamy, delicious flavors: original, vanilla, and chocolate.

Each tasty cup of Upright oatmilk packs the same key nutrients as dairy, without the unwanted allergens or environmental impact. Ready whenever and wherever you want it: just add water!

Uyen Tran, CEO
We want to create a new realm of materials.
Designing the future of sustainable biomaterial.
23 billion square feet global leather is produced annually, 90% of which uses heavy toxic chemicals for tanning and dyeing processes.

The TômTex mission is to create innovative material designs that parallel lifecycles observed in nature and serve as alternatives to the production methods that have contributed to our world’s environmental crisis. Our revolutionary bio-based materials offer a sustainable, accessible, and practical alternative to currently available commercial material options.

Meir Wachs, CEO
Heme iron proteins that transport oxygen are the proteins that give meat its meaty, umami flavor. They are what makes meat taste to us like meat. That is the crucial ingredient.
Transforming Meat Protein Production with Plants
Animal agriculture takes up 77% of all agricultural land on Earth despite supplying only 17% of humanity’s food supply.

Increasing awareness of animal agriculture’s impact on the environment together with wider consumer demand for natural health benefits and skepticism over meat supply chains has led to skyrocketing consumer demand for meat alternatives. However, along with higher lab production costs and complexity, the holy grail of taste, texture and relative cost remains elusive. Moreover, health concerns over processing have begun to percolate and questions over actual sustainability and clean labels remain.

Kyomei’s approach grew out of research at the University of Oxford and directly addresses these issues, innovating a novel animal protein production system using internal plant cell biology to produce natural and sustainable animal proteins. Kyomei produces proteins at scale, to power the next generation of meat alternatives.

David Bravo, Ph.D., CEO
Chronic pain is is not a one single disease: it is estimated 20 to 30% of the entire world's population suffers some levels of chronic pain.
Developing anti-addictive painkillers to save lives.
20 to 30% of the entire world's population suffers some levels of chronic pain.

Pannex Therapeutics is a pioneer biopharmaceutical company totally focused on the development of a novel therapeutic class of Pannexin 1 channel (Panx1) blockers. Pannex is developing a platform of small molecules that blocks this exciting new pharmacological target, Panx1 channels.

With potential applications in many therapeutic areas, the initial focus is on chronic pain treatment. The company is currently developing a first-in-class, selective and highly potent oral Panx1 channel blocker, for the treatment of chronic pain and prevention of opioid addiction.

Irina Miller, Ph.D., CEO
Skin is the biggest organ of the body, which means skin health is critical.
Defending skin against environmental and aging-related damage
Skin cancer incidence is rising 6% per year in all genders and ethnicities.

The cosmetic effects of ageing on skin and the development of skin cancers result from multiple changes in three types of skin cells (fibroblasts, keratinocytes, melanocytes) and degeneration of extracellular components (collagen, elastin). These changes are accelerated by toxic chemicals that are produced in skin when it is exposed to all wavelengths of sunlight, all common atmospheric pollutants, and tobacco smoke.

Kutanios is developing peptides to defend skin against these molecules by sequestering the damaging molecules and promoting their loss during the desquamation of surface cells. As the peptides are completely biodegradable and manufactured by green technology, they also protect the environment while protecting our skin.

Harvey Tian, Ph.D., CEO
A simple, streamlined, accessible technology is the way of the future for genomic analysis.
Next-Generation Sample Preparation. In Solution.
Changing 7 steps and 4 hours to a single step and 40 minutes, for scalable genomic DNA preparation.

Biological sample preparation has not kept pace with the dramatic changes in analytical techniques. Nowhere is this more evident than in DNA sample prep, which continues to be a low throughput process serving high throughput next-generation DNA sequencing. This mismatch is limiting the accelerated uptake of next generation sequencing.

Inso Bio envisions a future of increased accessibility, where complex sample prep protocols are completed from start to finish with the push of a button. This is why we are developing next-generation platforms to streamline workflows leading up to sequencing, to give people more time to devote to science, discovery, and data, rather than wrestling with their samples.

Poulami Chuadhuri, Ph.D., CEO
The moment we have a database with a significant amount of data correlating guide RNA, its on-target efficiency and the off-target effects, we are definitely going to fast track the entire development process of CRISPR based therapies.
Accelerating Gene-Editing Based Next-Generation Therapies
It costs $2 billion to develop a new gene-editing therapy, and $2 million to treat one patient.

Helex Bio enables gene therapy companies to design gRNAs & simulate outcomes of CRISPR edits to bring effective therapies to market faster with our Helex Platform™. The Helex Platform™ guides gene therapy companies in target identification, design and validation of efficient and safe gRNAs for creating functional impact with minimal significant off-targets. Additionally, the platform simulates edit outcomes to reliably develop therapy protocols.

The Helex Platform™ is powered by intelligent data driven deep-learning modeling using extensive high throughput next generation sequencing data derived from CRISPR edits on human cell lines. Helex not only gives reliable predictions through the Helex Platform™, but validate them in-house using cell-based assays and next generation sequencing to support with proven experimental data for high degree of reliability.

Danielle Rose, CEO
Our microbes basically act like an anti-anxiety medication for plants by regulating the stress that plants experience.
Helping global greenhouse vegetable growers increase crop yields with plant probiotics.
Ceragen increases greenhouse tomato yields by 20% with a single product application.

Ceragen is helping global greenhouse vegetable growers improve their plant’s microbiome to increase crop yields. Their first product is a plant growth promoting microbial inoculant that increases tomato yields up to 20% with a single application. Using their automated development pipeline, Ceragen is currently in the process of developing additional inoculants for use in other greenhouse vegetables. Ceragen’s inoculants are designed with the grower in mind, with a specific focus on ease of use and compatibility with all growing media and hydroponic systems.

Isabella Iglesias-Musachio
It takes on average 24 months to raise a cow for beef. By comparison, the Kinoko Labs product can be grown in less than 2 weeks, making it about 8000 times more time efficient to create than producing steak through traditional animal farming.
Kinoko Labs is a biotech company on a mission to create the next generation of meat alternatives, grown naturally from fungi.
The FAO reports that current meat production contributes 14-22% of the 36 billion tons of global CO2-equivalent greenhouse gases produced annually.

We all know the over consumption of animal products is a major cause of global warming and environmental degradation, and that the best way we can lower our carbon footprints is to switch to a plant-based diet. However, consumers are compromising on products that are ultra-processed, not necessarily healthy, and lacking variety: today’s meat-alternatives are mostly burgers, sausages & nuggets, and consumers lack ‘whole-muscle’ plant-based products.

The Kinoko Labs solution is to create healthier, nutrient-dense, and minimally processed whole-cut meat-alternatives, grown naturally from mycelium. By leveraging mycelium’s inherent structure, they can naturally replicate the texture of meat without the need for a long list of additives found in current meat alternatives. This means that we can create better-than-meat products that deliver on the entire taste experience, nutrition, and affordability without compromise.