Primary Bioscience is addressing one of biology’s biggest blind spots: we still can’t directly read proteins, the molecules that actually drive health and disease. Existing tools like mass spectrometry and DNA inference leave major gaps, missing key amino acids and chemical modifications that define protein function. Primary Bioscience is developing the first de novo protein sequencing instrument that reads single molecules end-to-end. By combining surface-enhanced Raman spectroscopy (SERS), innovative chemistry, and AI-based signal decoding, it captures all twenty amino acids and their modifications with single-molecule precision. This breakthrough enables true, full-coverage proteomics, unlocking discoveries in diagnostics, drug targets, and therapeutics that have been invisible until now.