Featured Trends
We’ve sliced and diced our portfolio into distinct “trends” that define our edge.
Climate 100
We are pleased to report that as of April 2021 the SOSV Climate Tech 100 have raised $1.85 billion from investors and have a market cap of $5.65 billion. The average company is four years old. SOSV (our parent fund) has invested $89 million in these companies and was in most cases the first investor, though we continued investing through early rounds.
IndieBio has never been one to shy away from the riskiest and most impactful investments for our planet. In fact, we embrace them.
Female Founder
Boosting female representation in the startup world is an ongoing challenge, but we’re dedicated to gender balance, not only because it’s the right thing to do, but because we would be dismissing impressive companies otherwise. We’ve found that more gender balance leads to better workplace culture and better ideas being exchanged.
Future of Food
It’s not just that we can make meat and fish in the lab, or with mushrooms and chickpeas. It’s not just that AI can predict the best plant ingredients to make the best tasting milk and yogurt. And it’s not just that yeast can be fermented to produce the healthier and better food preservatives. We’re diving deep every day into the foods that will satisfy novelty-seekers and conventionalists alike.
We’re putting big bets on the newest technologies and trends we think are ahead of the curve.
Future of Medicine
Medicine ain’t what it used to be. Today, bloodletting, skull-drilling and giving children cocaine for toothaches are relics of the past. Tomorrow, so too will addictive opioids, chemotherapy, and psychiatric drugs that are non-selectively bathing our bodies in chemicals.
The future of medicine is an exciting one, and we’re excited to share the most exciting technologies that enable the next wave of medicine and healthcare.
Impact
Our mission has always been Human and Planetary Health from the beginning, so it’s hard to say which of our companies are “impact” companies (in some ways, they all are).
Here, we narrowed down the startups that are directly addressing sustainability issues, improving public health, mitigating inequality, and democratizing access to infrastructure and technologies.
New Frontiers
Raising Now
Every season of the year, a new batch and about one-sixth of our alumni are in raise mode. These companies are currently raising and would love to talk to interested investors. We can set up those meetings or you can contact the companies directly.
Sustainable Solutions
If you’ve got an investment in a startup doing high-throughput AI + biology, your startup is probably spending way too much for having DNA variant libraries printed. Synplexity should be their vendor of choice. At the intersection of AI and biotech, there’s a bottleneck. It’s not the design function powered by AI to generate 10 […]
Dr. Sethi’s approach rewrites the entire treatment playbook. Her protocol deftly navigates the complex interactions between diet and psychiatric medications, optimizing treatment while minimizing side effects. She’s currently working with 30 lucky clients, who got ahead of the long waitlist, but she wants to scale her practice 1000-fold. Four major insurers have credentialed MPL, and […]
Bacterial biofilm will grow wherever there is moisture. That’s fine, until it becomes unruly: That’s when we call it biofouling. In offshore oil rigs, it’s a maintenance nightmare; in maritime shipping it’s a drag on efficiency; in industrial pipes and food processing, it’s a contamination hazard. All industries combined, biofouling is nearly $100 billion worth of […]
Ceal partners with seawater-cooled power plants to extract CO2 and calcium from the water running through the plant. It’s a win-win. By softening the water, the plant’s efficiency jumps by 4%. In an electrochemical process developed at Professor Charlotte Vogt’s lab at the Technion, the CO2 and calcium are transformed into calcium carbonate, which can […]
Based on 20 years of work at the University of Kentucky, and $11M in grants to bring it to commercial readiness, Phytogenesis is a fundamentally different solution for protecting the world’s crops from fast-evolving pathogens. For ag investors, the biocontrol market is structurally problematic, because a product that works in potatoes doesn’t then work for […]
Minutia is pioneering a functional cure for Type I Diabetes (T1D) that will allow patients to live without insulin injections and not suffer the long-term complications of the disease. Founded in 2021 out of UCSF, Minutia has already raised $13.5M, $6.5M in pre-seed SAFEs and $7M in grants, and has derisked the safety of their […]
Fermeate is the first startup in the world to apply optogenetics and photomolecular gene circuits to microbial based biomanufacturing. In plain English, they control gene activity with pulsed, programmed light. Developed over the past 11 years in the Avalos lab at Princeton, Fermeate is from the same academic lineage that inspired Prolific Machines, which we […]
Let’s talk DNA repair. Within 5 minutes of being in the sun, the energy of the solar photons introduces a small crack in the DNA of your skin cells. It’s not a random crack, it wears down the bonds at the 2 weakest points. One crack is called “CPD.” The other crack is called “6-4.” […]
The varroa mite is the leading cause of bee colony collapse. The current solutions aren’t good enough, or the problem wouldn’t exist. In the U.S., at least 45% of commercial colonies are infected with varroa; between 2023 and 2024, 55.1% died off. Unless we want food shortages and price spikes, the world needs a biopesticide […]
The global transition to net-zero emissions hinges on the mining of critical minerals, yet copper and lithium production, projected to grow 30% and 465% by 2050, will still fall short of meeting demand. Mining faces daunting challenges: 70% of copper remains locked in low-grade ores, and extracting it is increasingly uneconomical due to the massive […]