5h45 is a biotechnology company reinventing how we style and care for hair. Founded by Lea Majerholc after a near-fatal reaction to a chemical straightening treatment, 5h45 was born to end the cycle of toxic, damaging products that dominate an $80 billion market.

The company’s patented silk-based nanofilm forms a biomimetic layer around each hair fiber—shaping, repairing, and protecting it without harm. The result is smooth, frizz-free hair that resists humidity for months, yet remains fully reversible and biodegradable.

Led by scientists from Tufts, Technion, and Prose, 5h45 unites biotechnology and beauty to deliver the first safe, high-performance alternative to keratin and relaxer treatments.