Pesticides are always a compromise: if you kill the mosquitos, you end up killing the bees too. Pyrone discovered a rare natural compound that controls mosquitos and other pests not by killing them, but by temporarily stunning them. Already fast-tracked by the EPA and being tested by the USDA in Gainesville, Pyrone is now scaling […]

In the field of liquid biopsy, the abundance of new technologies are mere screening tests. They can’t monitor patients’ progression and drive clinical decisions. The real money is in monitoring disease patients, for years.  Atomic Force Microscopy scans the surface of cells at such high resolution that it can not only discriminate cancer cells from […]

Solid Ox is building Range Extenders for commercial fleets of electric trucks and buses. These range extenders use liquid fuel, where the CO2 is captured on board, right back into the fuel tank. Emissions-free.  Commercial fleets that need long range are very price sensitive to fueling costs. They also run day and night, so have […]

All  available  sunscreen  active  ingredients  absorb  through our  skin,  interfering  with  hormones  and  even  exacerbating UV damage. Meanwhile, SPFs in cosmetics,  washed down  the  drain at night,  accumulate  in  sensitive marine  environments,  where  even  the  “reef  safe”  versions threaten endangered corals and marine life. Based on groundbreaking work in protein engineering at Princeton, Soliome has […]

The market value of farmland is driven by yield. For example, increasing soy yield by 10 bushels an acre can double the value of the farmland. Puna Bio repairs soil health using extremophiles – organisms 3.5 billion years old, sourced from La Puna, the highest and driest desert on Earth. These organisms grow where others […]

Potassium controls every single heartbeat you have, but it’s the kidneys that control your potassium levels. You could say the kidneys are the gatekeeper to your heart. Kidney care is going through dramatic market disruption. Home dialysis is displacing clinics. And patient care management companies are siphoning off patients. Nevertheless, these patients are still ending […]

CellCrine discovered an enzyme that transforms cell culture for the cell-based meats industry. It’s made recombinantly, but can be used at such low concentration that only a tiny bit is needed. The impact is dramatic — reducing the need for insulin, transferrin, FGF2, TGFb, and other expensive media ingredients. The cells grow nearly as fast […]

Wayfinder has built a drug discovery platform for small molecules that modulate RNA targets. Their technology generates highly quantitative data on RNA-small molecules interactions at high-throughput. Combined with their AI/ML virtual screening models, they can search billions of molecules for RNA modulators in just 3 days. And they do it way faster than anyone else […]

Modern lifestyles are hard on our livers and kidneys, the organs that filter and break down metabolic waste products. But people don’t want to take drugs – they want to get healthy. Unlocked Labs unleashes the power of the microbiome to help out.  Unlocked is a consumer probiotic company that unlocks silent genes – regaining […]

There’s two general concerns around molecular farming, where animal proteins are grown in field crops. First, the extraction and purification. Second, the regulatory landscape for transgenic crops amidst other farmland.  Veloz Bio doesn’t use the farm. And the founders are experts at extraction and membrane purification. Without the need of bioreactors, they can develop and scale […]

All over Europe, people know the best tasting seaweed comes from Ireland. Sea & Believe founder Jennifer O’Brien walked every beach in Ireland, tasting the seaweed for her alternative seafood. She found one beach where the seaweed was remarkably tastier than all others. “It just had that distinctive spray of the ocean,” said O’Brien.  But […]

Photosynthesis wastes sunlight. Many scientific efforts are underway to reengineer photosynthesis to increase yields. Climate Crop – 5 years in the making at Weizmann Institute – will outgrow them all.  It works in all vascular plants. It’s simple – downregulating one enzyme. During the day, plants increase their storage of transient starch; at night, they […]

There’s thousands of ways that cells become unhealthy. But until 2012, there were only two ways that cells actually die. That year, the cofounder of Prothegen, Dr. Scott Dixon, discovered a new way cells die, called ferroptosis, an iron-mediated failure of antioxidant defenses. Now Dixon has partnered with Roche alum Davide Zanchi and chemist Derek […]