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Featured Trends

We’ve sliced and diced our portfolio into distinct “trends” that define our edge.

Featured Trends

Climate 100

We are pleased to report that as of April 2021 the SOSV Climate Tech 100 have raised $1.85 billion from investors and have a market cap of $5.65 billion. The average company is four years old. SOSV (our parent fund) has invested $89 million in these companies and was in most cases the first investor, though we continued investing through early rounds.

IndieBio has never been one to shy away from the riskiest and most impactful investments for our planet. In fact, we embrace them.

SEE 59 COMPANIES
Climate 100
We have always been climate first, and here are SOSV’s select 100 startups saving our planet
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Featured Trends

Female Founder

Boosting female representation in the startup world is an ongoing challenge, but we’re dedicated to gender balance, not only because it’s the right thing to do, but because we would be dismissing impressive companies otherwise. We’ve found that more gender balance leads to better workplace culture and better ideas being exchanged.

SEE 70 COMPANIES
Female Founder
42% of our companies are led by women, and they’re killing it
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Featured Trends

Future of Food

It’s not just that we can make meat and fish in the lab, or with mushrooms and chickpeas. It’s not just that AI can predict the best plant ingredients to make the best tasting milk and yogurt. And it’s not just that yeast can be fermented to produce the healthier and better food preservatives. We’re diving deep every day into the foods that will satisfy novelty-seekers and conventionalists alike.

We’re putting big bets on the newest technologies and trends we think are ahead of the curve.

SEE 33 COMPANIES
Future of Food
We’re seeing next biggest food trends that nobody else is seeing
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Featured Trends

Future of Medicine

Medicine ain’t what it used to be. Today, bloodletting, skull-drilling and giving children cocaine for toothaches are relics of the past. Tomorrow, so too will addictive opioids, chemotherapy, and psychiatric drugs that are non-selectively bathing our bodies in chemicals.

The future of medicine is an exciting one, and we’re excited to share the most exciting technologies that enable the next wave of medicine and healthcare.

SEE 50 COMPANIES
Future of Medicine
Imagine what medicine will look like just 10 years from now
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Featured Trends

Impact

Our mission has always been Human and Planetary Health from the beginning, so it’s hard to say which of our companies are “impact” companies (in some ways, they all are).

Here, we narrowed down the startups that are directly addressing sustainability issues, improving public health, mitigating inequality, and democratizing access to infrastructure and technologies.

SEE 41 COMPANIES
Impact
Deep science + Deep mission = Deep impact
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Featured Trends

New Frontiers

SEE 5 COMPANIES
New Frontiers
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Featured Trends

Raising Now

Every season of the year, a new batch and about one-sixth of our alumni are in raise mode. These companies are currently raising and would love to talk to interested investors. We can set up those meetings or you can contact the companies directly.

SEE 40 COMPANIES
Raising Now
These companies are currently raising and would love to talk to interested investors.
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Featured Trends

Sustainable Solutions

SEE 21 COMPANIES
Sustainable Solutions
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Category
Trends
Stage
Top Location
Cohorts
IBSF12 2021
Pyrone Systems

Pesticides are always a compromise: if you kill the mosquitos, you end up killing the bees too. Pyrone discovered a rare natural compound that controls mosquitos and other pests not by killing them, but by temporarily stunning them. Already fast-tracked by the EPA and being tested by the USDA in Gainesville, Pyrone is now scaling […]

HQ: United States
Ag Industrial Pre-Seed Sustainable Solutions San Francisco
IBSF12 2021
Cellens

In the field of liquid biopsy, the abundance of new technologies are mere screening tests. They can’t monitor patients’ progression and drive clinical decisions. The real money is in monitoring disease patients, for years.  Atomic Force Microscopy scans the surface of cells at such high resolution that it can not only discriminate cancer cells from […]

HQ: United States
Computational/AI Healthcare Pre-Seed Female Founder Future of Medicine Raising Now San Francisco
IBSF12 2021
Solid Ox Motors

Solid Ox is building Range Extenders for commercial fleets of electric trucks and buses. These range extenders use liquid fuel, where the CO2 is captured on board, right back into the fuel tank. Emissions-free.  Commercial fleets that need long range are very price sensitive to fueling costs. They also run day and night, so have […]

HQ: United States
ClimateTech Pre-Seed Climate 100 Raising Now Sustainable Solutions
IBSF12 2021
Soliome

All  available  sunscreen  active  ingredients  absorb  through our  skin,  interfering  with  hormones  and  even  exacerbating UV damage. Meanwhile, SPFs in cosmetics,  washed down  the  drain at night,  accumulate  in  sensitive marine  environments,  where  even  the  “reef  safe”  versions threaten endangered corals and marine life. Based on groundbreaking work in protein engineering at Princeton, Soliome has […]

HQ: United States
ClimateTech Consumer Healthcare Pre-Seed Raising Now Sustainable Solutions San Francisco
IBSF12 2021
Puna Bio

The market value of farmland is driven by yield. For example, increasing soy yield by 10 bushels an acre can double the value of the farmland. Puna Bio repairs soil health using extremophiles – organisms 3.5 billion years old, sourced from La Puna, the highest and driest desert on Earth. These organisms grow where others […]

HQ: Argentina
Ag ClimateTech Food Microbiome Seed Climate 100 Female Founder Future of Food Raising Now Latin America San Francisco
IBSF12 2021
ProtonIntel

Potassium controls every single heartbeat you have, but it’s the kidneys that control your potassium levels. You could say the kidneys are the gatekeeper to your heart. Kidney care is going through dramatic market disruption. Home dialysis is displacing clinics. And patient care management companies are siphoning off patients. Nevertheless, these patients are still ending […]

HQ: Canada
Biopharma Computational/AI Healthcare Pre-Seed Future of Medicine Raising Now Canada
IBSF12 2021
CellCrine

CellCrine discovered an enzyme that transforms cell culture for the cell-based meats industry. It’s made recombinantly, but can be used at such low concentration that only a tiny bit is needed. The impact is dramatic — reducing the need for insulin, transferrin, FGF2, TGFb, and other expensive media ingredients. The cells grow nearly as fast […]

HQ: United States
ClimateTech Food Pre-Seed Climate 100 Future of Food Raising Now San Francisco
IBSF12 2021
Wayfinder Biosciences

In the last few years, aptamers linked to CRISPR have brought programmable logic to drug design. However, the logic is primitive – once turned on, CRISPR remains on. Wayfinder is working on RNA-biosensors so that drugs can continuously sense their microenvironment, and turn modalities like CRISPR both on and off in response to what they […]

HQ: United States
Biopharma Computational/AI Industrial Pre-Seed Future of Medicine New Frontiers Raising Now San Francisco
IBSF12 2021
Unlocked Labs

Modern lifestyles are hard on our livers and kidneys, the organs that filter and break down metabolic waste products. But people don’t want to take drugs – they want to get healthy. Unlocked Labs unleashes the power of the microbiome to help out.  Unlocked is a consumer probiotic company that unlocks silent genes – regaining […]

HQ: United States
Consumer Healthcare Microbiome Pre-Seed Future of Medicine New Frontiers Raising Now
IBSF12 2021
Veloz Bio

There’s two general concerns around molecular farming, where animal proteins are grown in field crops. First, the extraction and purification. Second, the regulatory landscape for transgenic crops amidst other farmland.  Veloz Bio doesn’t use the farm. And the founders are experts at extraction and membrane purification. Without the need of bioreactors, they can develop and scale […]

HQ: Mexico
Ag ClimateTech Food Industrial Pre-Seed Climate 100 Future of Food Raising Now Sustainable Solutions Latin America
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